amjs澳金沙门
biomedical science and medicine

Our research has saved lives. We have innovated treatments for HIV, explored the origins of cancer, and created whole-body PET scans to better understand the human body.

图像
A woodcut illustration of a stethoscope

加速
抗癌药物

装备的年代. 林, a distinguished professor in the Department of Biochemistry and Molecular Medicine and the Sue Jane Leung Presidential Chair in Cancer 研究, invented the “one-bead-one-compound,或OBOC, combinatorial library method that allows for rapid synthesis and screening of millions of chemicals at a time to identify those that bind to diseased cells or endowed with specific biological or chemical properties.

图像
医用微珠

Expanding our understanding of
神经退行性疾病

In a study published in the journal Neurology in 2001, a amjs澳金沙门 MIND Institute team led by Randi Hagerman, Endowed Chair in Fragile X 研究, 描述了一种新的情况, fragile X-associated tremor/ataxia syndrome (FXTAS).

图像
Two chomosomes, the one in the foreground has a glowing red section

像解锁
动物疾病

在90年代早期, veterinary researchers at amjs澳金沙门 identified a similar viral disease in cats, which would become known as feline immunodeficiency virus. Today, researchers at amjs澳金沙门 use the SIV model to study treatments and vaccines for HIV/AIDS.

图像
一只坐着的虎斑猫

观察DNA
实时放松

Stephen Kowalczykowski and the late Ron Baskin in the College of Biological Sciences pioneered a technique for watching a single enzyme unwinding a DNA molecule in real time. The work has led to new discoveries in the mechanics of how DNA is copied and repaired, processes that are vitally important to understanding the origins of cancer and birth defects.

图像
DNA双螺旋结构

扫描全身
突然之间

While conventional PET scanners image the body as a series of slices, EXPLORER captures a detailed three-dimensional image of the entire body, dramatically reducing the time required for scans. This high-quality imaging enables better diagnostics and new studies, for example of how a drug is distributed through the body.

图像
Two dudes look through the opening of a full body PET scanner

寻找更好的方法
治疗艾滋病毒

Satya Dandekar's lab was the first to show the benefit of initiating antiretroviral therapy in the early stages of HIV infection, leading to rapid immune recovery and better control of the viral infection. The findings supported changes in the treatment protocols for HIV to start anti-HIV therapy early in HIV infection to achieve better clinical outcomes.

图像
Internal view of human digestive organs

更多来自amjs澳金沙门